Wei Shen, M.D., M. S.

Obesity Research Center
1090 Amsterdam Ave., 14D
New York, NY 10025

Phone: (212) 523-1738
Fax: 212-523-3571
E-mail: ws2003@columbia.edu

Professional Experience

2004- presentAssociate Research Scientist, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY
2004- presentResearch Associate, Obesity Research Center, St. Luke's-Roosevelt Hospital, New York, NY
2001 - 2004Postdoctoral Research Fellow, Obesity Research Center, St. Luke's-Roosevelt Hospital & Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY
2000Visiting Scholar, Children's Hospital of Philadelphia, Philadelphia PA
1999 - 2000Chief Resident, Department of Pediatrics, (PUMCH), Beijing
1997 - 1999Resident, Department of Pediatrics, PUMCH, Beijing

Professional Memberships

Awards

Reviewer for Peer Reviewed Journals

Grant Support

Co-Investigator
R21 DK66360-01 (S.B. Heymsfield, M.D., P.I.)
NIH/NIDDK MRI Visceral Adipose Tissue Partitioning: Advanced Models
12/2003 - 11/2006
Principle Investigator of Core B
PO1-DK42618 (PI: D. Gallagher)
NIH-NIDDK Program Project Grant
Body Composition: Methods, Models, & Clinical Application
Core B: Magnetic Resonance Imaging and Spectroscopy
07/2005 - 06/2007
Co-Investigator
ADA Research Award (J. Albu, M.D., P.I.)
Intramyocellualr lipid: effects of race and diets
01/2005 - 12/2007
Co-Investigator
P30 DK26687 (D.C. Shungu, Ph.D., P.I.)
NIH/NIDDK Pilot grant of Obesity Research Center
1H Magnetic Resonance Spectroscopic Imaging of Intramyocellular Lipid Metabolism
09/2003 - 08/2005

Publications

    A. Peer-reviewed Publications

  1. Shen W, Liu H, Punyanitya M, Chen J, Heymsfield SB. Pediatric obesity phenotyping by magnetic resonance methods. Curr Opin Clin Nutr Metab Care. 2005 Nov;8(6):595-601.
  2. Shen W, Punyanitya M, Wang ZM, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S Visceral Adipose Tissue: Relationships Between Single Slice Areas and Total Volume American Journal of Clinical Nutrition 2004;80:271-8
  3. Shen W, Punyanitya M, Wang Z, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S. Total Body Skeletal Muscle and Adipose Tissue Volumes: Estimation from a Single Abdominal Cross-Sectional Image. Journal of Applied Physiology 2004;97: 2333-2338
  4. Shen W, St-Onge MP, Pietrobelli A, Wang J, Wang ZM, Heshka S, Heymsfield SB. Four-Compartment Cellular Level Body Composition Model: Comparison of Two Approaches Differing in Cost and Availability Obesity Research 2005;13(1):58-65
  5. Shen W, Wang ZM, Tang H, Heshka S, Punyanita M, Zhu S, Lei J, Heymsfield SB. Volume Estimates Derived In Vivo by Imaging Methods: Model Comparisons With Visible Woman as the Reference. Obesity Research 2003;11: 217-225
  6. Shen W, Wang ZM, Punyanita M, Lei J, Sinav A, Kral JG, Imielinska C, Ross R, Heymsfield SB. Adipose Tissue Quantification by Imaging Methods: A Proposed Classification. Obesity Research 2003, Vol. 11, Jan, pp5-16
  7. Shen W, Mao XL, Wang ZM, Punyanitya M, Heymsfield SB, Shungu DC. Measurement of Intramyocellular Lipid Levels with 2-D Magnetic Resonance Sepctroscopic Imaging at 1.5 T. Acta Diabetologia. 2003;40:S51-S54
  8. Jones Jr. A, Shen W, Gallagher D, Heshka S, Marie-Pierre St. Onge, Wang ZM, Heymsfield SB African American-Caucasian Female Body Composition Differences: Relationship to Resting Energy Requirements American Journal of Clinical Nutrition 2004; 79: 780-786
  9. Wang Z, Heshka S, Heymsfield SB, Shen W, Gallagher D. A Cellular Level Approach to Predicting Resting Energy Expenditure Across The Adult Years American Journal of Clinical Nutrition 2005;81(4):799-806
  10. Zhu SK, Heshka S, Wang ZM, Shen W, Allison DB, Ross R, Heymsfield SB. The association of combined measure of body-mass index and waist circumference with metabolic risk factors: A new criteria for weight management. Obesity ResearchI 2004 ;12:633-645.
  11. Zhu SK, Wang ZM, Shen W, Heymsfield SB, Heshka S. Percent Body Fat Ranges Associated with Metabolic Syndrome Risk: Results Based on the Third National Nutrition and Health Examination Survey (1988-94). American Journal of Clinical Nutrition 2003;78: 228-35.
  12. Wang ZM, Shen W, Kotler D, Heshka S, Wielopolski L, Aloia JF, Nelson ME, Pierson Jr. RN, Heymsfield SB. Total-Body Protein: A New Cellular Level Mass and Distribution Prediction Model American Journal of Clinical Nutrition 2003;78: 979-84.
  13. Lee RC, Heymsfield SB, Shen W, Wang ZM. Total-Body and Regional Skeletal Muscle Mass Measurement Methods: An Overview International Journal of Body Composition Research 2003;1:93-102
  14. Kim J, Heshka S, Gallagher D, Kotler DP, Mayer L, Albu J, Shen W, Freda PU, Heymsfield SB. Intermuscular Adipose Tissue-Free Skeletal Muscle Mass: Estimation by Dual-Energy X-Ray Absorptiometry in Adults (Journal of Applied Physiology 2004;97:655-60. Epub 2004 Apr 16)
  15. St-Onge MP, Wang J, Shen W, Wang ZM, Allison DB, Heshka S, Heymsfield SB. Dual-Energy X-Ray Absorptiometry-Measured Lean Soft Tissue Mass: Differing Relation to Body Cell Mass Across the Adult Lifespan J Gerontol A Biol Sci Med Sci. 2004 Aug;59:B796-800
  16. Silva AM, Shen W, Wang ZM, Aloia JF, Nelson ME, Heymsfield SB, Sardinha LB, Heshka S. Three-Compartment Model: Critical Evaluation Based Upon Neutron Activation Analysis Am J Physiol Endocrinol Metab. 2004;287:E962-9
  17. Shen W, Dong M, Wei M. A retrospective study of 93 cases with hepatomegaly. Chinese Journal of Pediatrics, Feb. 2000, Vol 38, pp68~71.
  18. Shen W, Chen YH, Li WZ. The pathogenesis of congestive heart failure associated with bronchopneumonia. Chinese Journal of Pediatrics, Mar. 1998, Vol. 36, pp175~7.
  19. Shen W, Chen YH, Li WZ. The pathogenesis and mechanism of digoxin treatment in bronchopneumonia associated with congestive heart failure. Journal of Beijing Medical University, Aug. 1998, Vol. 30, pp323~5.
  20. Shen W, Wang DH, Zhao SM. The physiology effects and clinical applications of high frequency ventilation. Foreign Medical Sciences (Pediatrics subdivision), Jan. 1999, Vol. 26, pp7~11.
  21. Shen W, Wang DH. Breast-feeding and infectious diseases. Chinese Journal of Perinatal Medicine, Nov. 1999, Vol. 1, pp182~4.

    B. Conference proceedings

  22. Jin Y, Imielinska CZ, Laine A, Udupa J, Shen W, Heymsfield SB Segmentation and Evaluation of Adipose Tissue from Whole Body MRI scans. Medical Image Computing and Computer Assisted Intervention (MICCAI) Montreal, Canada 2003 Proceedings; pp635-642

    C. Book chapters

  23. Shen W, St-Onge M-P, Wang ZM, Heymsfield SB. Chapter 1. The Science of Body Composition Research. In Heymsfield SB, Lohman T Wang Z, Going SB Human Body Composition Human Kinetics, Champaign, IL, 2005
  24. Wang ZM, Shen W, Withers R, Heymsfield SB. Chapter 12. Multicomponent Molecular-level Models of Body Composition Analysis. In Heymsfield SB, Lohman T, Wang Z, Going SB Human Body Composition Human Kinetics, Champaign, IL, 2005
  25. Sopher A, Shen W, Pietrobelli A. Chapter 9. Pediatric Body Composition Methods. Heymsfield SB, Lohman T, Wang Z, Going SB Human Body Composition Human Kinetics, Champaign, IL, 2005
  26. Heymsfield SB, Baumgartner RN, Allison DB, Shen W, Wang ZM, Ross R. Chapter. 2, Evaluation of total and regional adiposity. In: Bray GA, Bouchard C, James WPT, (Eds) Handbook of Obesity. Marcel Decker, Inc., New York, 2003
  27. Restrepo PE, Wang ZM, Shen W, Heymsfield SB. Chapter 11. Evaluation and Monitoring of the Obese Patient's Body Composition (pp103-121). In Barranco JG (Eds) Obesity. McGraw-Hill, New York, 2003
  28. Hoffman DJ, Huber-Miller RK, Allison DB, Wang ZM, Shen W, Heymsfield. Chapter 5. Human Body Compostition (pp103-127). In: Obesity: Mechanisms and Clinical Management. Lippincott Williams & Wilkins, New York, 2002
  29. Wei M, Shen W. Chapter 2, Pediatric Connective Tissue Diseases (pp299-310) in Yu MX, et al. Diagnostic & Therapeutic Handbook of Modern Rheumatic Diseases. China Peking Union Medical College Publisher, Beijing, 2000.
  30. Zhu CY, Shen W. Chapter 4, Rheumatic Fever (pp328-336) in Yu MX, et al. Diagnostic & Therapeutic Handbook of Modern Rheumatic Diseases. China Peking Union Medical College Publisher, Beijing, 2000.

    D. Case Report

  31. Xu RF, Shen W. Congenital factor VII deficiency associated with pulmonary hemosiderosis. Chinese Journal of Pediatrics, Apr. 1997, Vol. 35, pp205

    E. Published Abstracts

  32. Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer FX, Heshka S, Heymsfield SBA Single Upper Abdominal Image Slice Has a Higher Metabolic Syndrome Prediction Value than the Traditional L4-L5 Slice The North American Association for the Study of Obesity, Vancouver, Canada, 2005 701-P
  33. Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer FX, Heymsfield SB, Heshka S Waist Circumference Has a Higher Predictive Value for Metabolic Syndrome Than Percentage Fat The North American Association for the Study of Obesity, Vancouver, Canada, 2005 24-OR
  34. Chen J, Shen W, Punyanitya M, Horlick M, Gallagher D, Heymsfield SB, Heshka S. Tissue Volume Estimates Derived by Magnetic Resonance Imaging (MRI): Validity of Different Slice Interval Protocols in Children The North American Association for the Study of Obesity, Vancouver, Canada, 2005 248-P
  35. Shen W, Punyanitya M, Chen J, Horlick M, Gallagher D, Heshka S, Heymsfield SB Visceral Adipose Tissue: Relationships Between Single Slice Areas and Total Volume in Children Seventh International Symposium In Vivo Body Composition Studies linking structure & function (BC2005), Southampton, UK 2005 O-23
  36. Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer FX, Heymsfield SB, Heshka S Health Risk Indicators Correlate Better with a Single Upper Abdominal Image Slice Than With the L4-L5 Slice International Symposium In Vivo Body Composition Studies linking structure & function (BC2005), Southampton, UK 2005 P-61
  37. Shen W, Mao X, Wolper C, Dashnaw S, Hirsch J, Heymsfield SB, Shungu DC Variation of Measurements of Intramyocellular Lipid Levels by Single- and Multi-voxel MRS in Overweight and Lean Subjects During Controlled Dietary Fat Intake International Symposium In Vivo Body Composition Studies linking structure & function (BC2005), Southampton, UK 2005 O-16
  38. Shen W, Mao X, Wolper C, Dashnaw S, Hirsch J, Heymsfield SB, Shungu DC Reproducibility of Measurements of Intramyocellular Lipid Levels by Single- and Multi-voxel MRS in Overweight and Lean Subjects During Controlled Dietary Fat Intake International Society for Magnetic Resonance in Medicine 13th Scientific Meeting, Miami, Florida 2005 (Oral presentation, abstract number 800)
  39. Shen W, Punyanitya M, Wang ZM, Gallagher D, St-Onge MP, Albu J, Pi-Sunyer FX, Heshka S, Heymsfield SB. Waist Circumference Correlates with Metabolic Syndrome Indicators Better Than Percentage Fat. Federation of American Societies for Experimental Biology (FASEB) San Diego CA, USA, 2005 Abstract number 2641
  40. Shen W, Punyanitya M, Gallagher D, Heshka S, Heymsfield SB Is Percentage Fat More Useful than Anthropometrics? Correlations with Metabolic Syndrome The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 881-P
  41. Shen W, Punyanitya M, Gallagher D, Heshka S, Heymsfield SB Regional Adiposity and Metabolic Syndrome Components: Modeling of Associations Based on Whole-Body Magnetic Resonance Imaging in a Large Caucasian Sample The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 672-P
  42. Shen W, Punyanitya M, Wang ZM, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S Total Body Skeletal Muscle and Adipose Tissue Volumes: Estimation from a Single Abdominal Cross-Sectional Image The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 499-P
  43. Shen W, Belloso WH, Wang J, Wang ZM, Punyanitya M, Heshka S, Heymsfield SB Subcutaneous Adipose Tissue (SAT): Prediction From Skinfold Measurements The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 884-P
  44. Shen W, Albala B, Wang ZM, Heshka S, Heymsfield SB Percent Body Fat: Prediction From NHANES Skinfold Measurements The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 886-P
  45. Asare NK, Shen W, Punyanitya M, Horlick M, Gallagher D, Heymsfield SB, Heshka S Tissue Volume Estimates Derived In Vivo by Magnetic Resonance Imaging (MRI): Validity of 5 cm Slice Protocol in Children The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 45-OR
  46. Pietrobelli A, Wang Z, Wang J, Horlick M, Heshka S, Shen W, Heymsfield SB. Skeletal Muscle Mass in Pediatrics: Prediction from Total Body Potassium. The North American Association for the Study of Obesity, Las Vegas, USA, 2004 Abstract number 227-P
  47. Shen W, Punyanitya M, Wang ZM, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S Visceral Adipose Tissue: Relationships Between Single Slice Areas and Total Volume. Federation of American Societies for Experimental Biology (FASEB) Washington DC, USA, 2004 Abstract number 826.5
  48. Heshka S, Punyanitya M, Shen W, Chatterjee P, Gallagher D, Albu J, Allison DB, Heymsfield SB Inter-Reader Reliability in Reconstructing Tissue Volumes from Magnetic Resonance Images Federation of American Societies for Experimental Biology (FASEB) Washington DC, USA, 2004 Abstract number 139.3
  49. Kim J, Heshka S, Gallagher D, Kotler DP, Mayer L, Albu J, Shen W, Freda PU, Heymsfield SB Inter- and intra-muscular Adipose Tissue-Free Total-body Skeletal Muscle Mass: Estimation by Dual-Energy X-Ray Absorptiometry Images Federation of American Societies for Experimental Biology (FASEB) Washington DC, USA, 2004 Abstract number 374.3
  50. St-Onge MP, Wang J, Shen W, Wang ZM, Allison DB, Heshka S, Heymsfield SB. Dual-Energy X-Ray Absorptiometry-Measured Lean Soft Tissue Mass: Differing Relation to Body Cell Mass Across the Adult Lifespan Federation of American Societies for Experimental Biology (FASEB) Washington DC, USA, 2004 Abstract number 347.7
  51. Asari NK, Shen W, Punyanitya M, Horlick M, Gallagher D, Heymsfield SB, Heshka S. Volume Estimates Derived In Vivo by Magnetic Resonance Imaging (MRI): Validity of 5 cm Slice Protocol in Children 13th European Congress on Obesity, Prague, Crech Republic, 2004.
  52. Freda PU, Geer EB, Shen W, Heymsfield SB. Body composition assessed by total body MRI in patients with Active Acromegaly. The Endocrine Society's 86th Annual Meeting, New Orleans, USA, 2004.
  53. Shen W, Punyanita M, Heshka S, Heymsfield SB. High Resolution Magnetic Resonance Imaging Successfully Separates Regional Abdominal Adipose Tissue. The North American Association for the Study of Obesity, Florida, USA, 2003 Abstract number 219-P
  54. Shen W, Punyanita M, Wu K, Huang X, Heshka S, Heymsfield SB. High Resolution Magnetic Resonance Imaging in Quantification of Intra- and Peri-muscular Adipose Tissue in the Leg Region. The North American Association for the Study of Obesity, Florida, USA 2003, Abstract number 219-P
  55. Wang ZM, Shen W, Heshka S, Heymsfield SB Total-Body Protein: A Cellular Level Mass and Distribution Prediction Model. The North American Association for the Study of Obesity, Florida, USA 2003
  56. Shen W, Zhu SK, Wang ZM, St-Onge M-P, Punyanita M, Heymsfield SB, Heshka S. High correlation between single slice area and multi-slice volume imaging of the abdominal region despite high intra-subject between-slice variability in visceral adipose tissue. Federation of American Societies for Experimental Biology (FASEB), San Diego, USA, 2003, Abstract number 452.5
  57. DeNino WF, Shen W, Guo EX, Sun AJ, Chua SC, Heymsfield SB Leptin Receptor: Effects of Knockout and Transgene Insertion on Body Composition and Bone Properties in the db/db Model. Federation of American Societies for Experimental Biology (FASEB) San Diego, USA, 2003, Abstract number 706.13
  58. Asari N, Mayer L, Shen W, Wang ZM, Levin N, Kaysen G, Heymsfield SB. Total body skeletal muscle mass: evaluation of total body potassium (TBK) prediction model in renal failure and anorexia nervosa patients. Federation of American Societies for Experimental Biology (FASEB) San Diego, USA, 2003 Abstract number 707.12
  59. Jones AJr., Shen W, Rubiano F., Zhu SK, Punyanitya M, Heymsfield SB. Visceral adipose tissue prediction: are there race differences after controlling for waist circumference and age? Federation of American Societies for Experimental Biology (FASEB) San Diego, USA, 2003 Abstract number 452.3
  60. Shen W, Shungu DC, Mao X, Wang ZM, Heymsfield SB. Quantifying intramyocellular lipid levels by two-dimensional magnetic resornance spectroscopy on 1.5 Tesla magnetic resonance imaging system. The Sixth International Symposium on Body Composition Studies, Rome, Italy, 2002.
  61. Mayer L, B. Walsh T, Gallagher D, Heymsfield SB, Shen W, Glasofer D. Body Fat Distribution Is Abnormal Despite Normalized Weight in Women with Anorexia Nervosa. Submitted to Eating Disorders Research Society.
  62. Shen W, Wang ZM, Tang H, Heshka S, Zhu S, Heymsfield SB. Comparison of two geometric models of estimating tissue volumes: Validation by segmentation of visible women. Nineth International Congress on Obesity, Sao Paulo, Brazil, International Journal of Obesity Relat Metab Disord, 2002;26:S32.
  63. Wang ZM, Zhu S, Shen W, Heymsfield SB. Skeletal muscle mass of overweight and obese adults: Prediction from total-body potassium. Ninth International Congress on Obesity, Sao Paulo, Brazil, International Journal of Obesity, 2002;26:S32.
  64. Tang H, Wu EX, Shen W, Gallagher D, Heymsfield SB. Body composition by magnetic resonance imaging: new software approach. First Annual Nutrition Week: A Scientific and Clinical Forum and Exposition, San Diego, 2002. American Journal of Clinical Nutrition 2002;75:358S.
  65. Shen W, Punyantia M, Lei J, Wang ZM, Heymsfield SB. Visceral adipose tisuue: Inconsistent measurement definition in published literature. North American Association for the Study of Obesity, Canada: Quebec City, 2001. Obesity Research 2001; 9:165S. First Annual Nutrition Week: A Scientific and Clinical Forum and Exposition, San Diego, 2002. American Journal of Clinical Nutrition 2002;75:352S.

    F. Others

  66. Heymsfield SB. Wang ZM, Shen W. Body composition in pediatrics to geriatrics: a lesson for nutritional monitoring. Nestle Nutrition Workshop Series Clinical & Performance Program. 2002;7:239-50; discussion 250-5.